Can I live and work anywhere in Australia on a subclass 190 visa, or am I tied to the nominating state?

Legally, the Skilled Nominated visa (subclass 190) is a permanent residence visa. Once granted, your visa conditions do not lock you to a specific region, so you have full work rights across Australia.

However, when a state or territory nominates you, they usually ask you to declare an intention to live and work in their area, and some have commitment expectations. Breaking that commitment will not normally cancel a granted permanent visa, but it can affect goodwill and future dealings with that state. Read your nominating state's specific requirements before you accept the nomination.